Another great 
audio interview in the NEJM this week.
Arrow KJ, Gelband H, Jamison DT.  Making Antimalarial Agents Available in Africa. N Engl J Med. 2005 Jul 6
The Africa Malaria Report 2003 prepared by UNICEF shows that Africa's population carries the largest burden of malaria cases in the world, and the barrier to treating those that have the disease is cost. It's no wonder, with Africa being home to come of the poorest of poor in the world. And now, across Africa, malaria has become resistant to chloroquine - the cheaper antimalarial. The alternative - artemisinins which are widely used in Asia, and very expesive by comparison.
The solution propoes by the Institute of Medicine is to "allow subsidies to enter at a high international
 level — at the top of the distribution chain. ... The drugs would then flow down to the end
 users through the same pathways as chloroquine now does, with
 the requisite profit margins being taken where the private sector
 now operates. If these drugs start at a very low price when
 they enter the supply chain and if their supply is adequate,
 the price to consumers should be about the same as the current
 price of chloroquine."
Read the story, or 
listen to the interview, it's heartbreaking.