Combined Tetanus, Diphtheria, and 5-Component Pertussis Vaccine

Increasing reports of pertussis among US adolescents, adults, and their infant contacts have stimulated vaccine development for older age groups. A intramuscular 0.5 ml dose of either Tdap or tetanus-diphtheria vaccine (Td) was given to adolescents and adults aged 11 - 64 years.

Conclusions "This Tdap vaccine elicited robust immune responses in adolescents and adults to pertussis, tetanus, and diphtheria antigens, while exhibiting an overall safety profile similar to that of a licensed Td vaccine. These data support the potential routine use of this Tdap vaccine in adolescents and adults."

This is an early release article found in JAMA.
Read the entire article:
Pichichero, Michael E. et al. Combined Tetanus, Diphtheria, and 5-Component Pertussis Vaccine for Use in Adolescents and Adults JAMA published 2 June 2005